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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. The risk of HbS polymerization is enhanced by a low (acid) pH, a state of dehydration, and increased levels of
2,3-DPG. Increased temperature (above 37°C) also adds to the risk.
Hematology
Which group of conditions INCREASES the risk of HbS polymerization?

A) Alkaline pH, dehydration, increased level of 2,3-DPG
B) Acid pH,dehydration, increased level of 2,3-DPG
C) Alkaline pH,dehydration, decreased level of 2,3-DPG
D) Acid pH, dehydration, decreased level of 2,3-DPG

2. Macroamylasemia can be diagnosed by measuring amylase levels in the urine and serum. In patients with macroamylasemia, there will be high levels of amylase in the serum. However, macroamylasemia can look similar to acute pancreatitis, which also causes high levels of amylase in the blood. To help differentiate, we measure amylase levels in the urine. Urine levels of amylase are low in people with macroamylasemia, but high in patients with pancreatitis.
The results which would be MOST consistent with macro-amylasemia are?

A) Increased serum amylase and normal to low urine amylase values
B) Increased serum and increased urine amylase values
C) Normal serum and normal urine amylase values
D) Normal serum amylase and elevated urine amylase values

3. Hemolytic transfusion reactions seldom occur because the incidence of unexpected antibodies in random patients is relatively low, e.g., 3-5% is sometimes cited.
Being transfused with O Rh negative RBC is irrelvant if you have an unexpected antibody like anti-K or anti-c.
Incompatible red cells may "bleed out" but only if bleeding is brisk. Even then, a hemolytic reaction may occur later once the patient's antibody rebounds and destroys remaining antigen-positive donor red cells.
It's true that some patients have only cold-reactive antibodies that will not react at body temperature. But this does not explain why warm-reactive red cell antibodies cause few reactions Why do so few patients transfused with un-crossmatched red cells in an emergency experience a hemolytic transfusion reaction? Select the one best reason.

A) Some patients have cold-reactive antibodies that will not react at body temperature.
B) They usually receive group O Rh negative red cells; a hemolytic transfusion reaction will never occur if O Rh-negative red cells are transfused.
C) They hemorrhage so severely that incompatible donor red cells "bleed out" before a reaction occurs.
D) The incidence of unexpected red cell antibodies is relatively low.

4. The creatinine clearance for this patient is 100 mL/min.
Creatinine clearance values are calculated using the following equation:
Creatinine Clearance (mL / min) = (Urine Creatinine / Serum Creatinine) x Urine Volume (mL) / [ time (hr) x
60 ]
For this patient Creatinine clearance (mL/min)= (120/1.5) x (1800 / [24 x 60])
80 x 1800/1440, which is 80 x 1.25, or 100 mL/min
A 45-year-old male of average height and weight had a serum creatinine of 1.5 mg/dL and urine creatinine was
120 mg/dL; the total volume of urine collected over a 24-hour period was 1,800 mL. Calculate the creatinine clearance for this patient in mL/min.

A) 56
B) 144
C) 100
D) 225
E) 177

5. The conidia of Exophiala species are produced within phialides that extrude the conidia in tight, ball-like clusters.
The large, drum stick-shaped muriform macroconidia of Alternaria species are arranged in short chains; the small, elliptical conidia of Cladosporium species are arranged in both long and short, branching chains.
Which of the following dematiaceous fungal species produce conidia in clusters?

A) Exophiala species
B) Alternaria species
C) Cladosporium species

Solutions: